Schizophrenia is a mental illness characterized by disturbances in thinking and perception, which manifest as hallucinations (e.g., hearing voices) and delusions (positive symptoms). At the same time, the illness leads to a loss of motivation, emotional flatness, and social withdrawal (negative symptoms). The illness often begins gradually. Those affected frequently withdraw socially over the course of years, neglecting education and hobbies and appearing emotionally flat, before the first psychotic episode occurs.
Typical negative symptoms often begin in men during late adolescence to early adulthood (ages 15–25) and in women typically five years later (ages 20–30). The first psychotic symptoms usually appear after three to five years.
Schizophrenia is a chronic illness that typically requires lifelong treatment with antipsychotic medications, combined with psychotherapeutic care and social rehabilitation.
The prognosis for schizophrenia generally follows the rule of thirds: One-third of those affected recover completely, one-third experience a phased course with residual symptoms, and the final third suffer from a persistent chronic condition. A spontaneous recovery is extremely rare; instead, an early combination of medication, psychotherapy, and support is crucial to reduce the relapse rate from over 80% to under 30%.
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